SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d28f7c645905cc88420408b842773bbb67a81219be35df718f13a704261b638' 
  AND token = 'b9AOMOgMX5SrKLaqv6sQE1XrhzHPXk4beLR+zteow5s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}