SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf153864a6922a75802a657402a1d350c4190e31771f5faac764060886e6574c' 
  AND token = 'awP3T33lBtQjtstV2sjYynH7nmTeh2oMVKYQR9SxKeo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}