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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ffa43eedc32884a307f0ab72b803918fe5496d81c59177a5e08d3bea9a7b240' 
  AND token = 'z6EkbyUh/5e82vP38rwlpBGuLZeTGDcDOkESSLSI8mM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}