SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1fddcdd369447e57ac4c08fae49acdd90ca33091edca4eb95aa1f2f7aad1c3b' 
  AND token = '8o7xR6RZxkuE2cQXzCN1bmq2XzEXLW4PkJWdMWX6+b8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}