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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fee0e0c196f8c7d66b9a4c84bf4dc7c52bc10696926ccf14cde95892259369d' 
  AND token = 'QDQDkAr07ILfW8MDrp6k9O5ZIoE3D+3B8k8ap88ltJU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}