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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70008e00da90f594f67584daf979b60cd39c57757a80438025432f458205f96b' 
  AND token = 'sD/Sj/INhwjse0otJwo18BKbdKKxQqS5OCRvu6D8r6c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}