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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2889e21d729622e639dab96f9a759ca4116fa3cf9a2b9003bd36587c5103a2a5' 
  AND token = 'JZktOPoD3a95cfGWsPgnYXFzQ5Oe38kP8hcRJp8SWm4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}