SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54d9aa14f1c2464793d55299463323316231a2c0b04994a556f651be946e834f' 
  AND token = '6wtf/yg1Uc6NvI96dBvwhywHJhJ73jgxL4AEO9MNSQo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}