SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd61d623a1ada5e70542efd9997e93f6286201b4d1d1f6fc0836d81b44cacce1' 
  AND token = 't6xX4fnJqwpx05SHSJTgxCSSf5nPeG28VL3glRxNhw4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}