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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '427a8e883faaee66654da65598095b9e33237a624d751e37249b4f07c52ffdb1' 
  AND token = '+j4BboYrDjp02pS4n8RcsCGObH/artX++PMNVsI/W8E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}