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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '441a2eed6281840abb0f74f8dba440535d1bb9aafe5bb8ffdd5f2f1560aace60' 
  AND token = 'i3qu4wjKCIqC9Bc8xUtC0x3D6JQejiObZ9MXLw0u5zY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}