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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65dd24ce08a851c411a3eb64e3dfa51db121479ec755dfbc1a0938c4fe850a6f' 
  AND token = '9PNi01AqKEgDOJ2MgF3hXYdIxL1AzJ8wdmKsc4sTCZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}