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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '121e1ac24b02a23745f6ef2159a9a755e86a7f633b6ec3f13e09055228678e2e' 
  AND token = 'ZwycBiTBtGU3qiyD9ugTERiqYn4s1n8XjMbFmFsrvdA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}