SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '741e4a3193aef3b26bd233247f73b8eb07f0809d31a989eda9a674a98a7aa9f9' 
  AND token = 'dBabQwXvIJ7fv0LVc2+VgeJzl9BWXpNpCU8yjsZvsDc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}