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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3466146718a25fb17d1d342e30721676fe7cd2d441f13153013e4d18c737892b' 
  AND token = 'i/4BcZP8fyPaD3zwg11yJImJMyOfVZOvfje/IxFheb4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}