SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f58c1445754791e4a8ca746cd8ae9d08d78dc9d12db6d3c8e26a53163cbf617b' 
  AND token = 'nRLzMQry9MfTHTxkdeR1lMY4pgEHGzgJjLhhSNqztTw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}