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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b124e4dffb47a26911fc28616a2cded5978da836a7362514358e52ed46c9194e' 
  AND token = 'AFR14x1XriFSq74f0yM+32JfFphu31SqVAPZfgJiCaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}