SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59cdba5d05e815f0f0d19071a2122b80db92233b957700400a28459a3b5206a6' 
  AND token = 'RNnQ+kMcefK/WeuKB2t3ga8DP0vMaOzYr5phKHIfvBk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}