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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7e764eaaeef0fbfd67d8bd06546dff07060f2f61e358d67af0b533394694b11' 
  AND token = 'Nltj7VRzoM0+AEbKn2H7MbM+ZLAY/PwQ4OrwS2BvLQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}