SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '456e1585c5ec7e98fb895a70204176f0b9e20ed0de8602d05c687ba165d3090c' 
  AND token = 'yzknvrqCys4wXI5qbVmmBZEveSWiuVtE6p+aTsCco3s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}