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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4b2680abe5decf078651e2aa80ce51642afcc5c120474e882e43f145e4b62db' 
  AND token = 'U094UDbV8zW2em9E04U+ajqWOIey0sWQtdlkzrJOJic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}