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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '476c2d216ce5bece483e677f3f0507d4c48471cd88c9df6c7a85429617e874ad' 
  AND token = 'FxqgWL7+CtzS5DCE8tdA5yvgecJXMTDYmfDs2wi3+ww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}