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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd551f1a92688f118e47d16caf4bad9993ca53bc6137bbbca6e39224c15635508' 
  AND token = 'wcOI5I2HlGPJ0rrVwvSBvWUtBI0I+vRdCBPdHyO8aP0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}