SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d2e8bb1fcbd62aa0fc7b500ca9b3efa100380336d9ade2db2ac9e2747fbf10c' 
  AND token = 'w2aIY6YyEbnasEgjp3QN4gtm06Dk/Ejl+ICIwWKh5uc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}