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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b332fc3722d9d7595c318f0d763afd3ece8db3f5c7fb29e6b20264ff492f1c9' 
  AND token = 'NXKlGV054rPVG+SoiTiDzQTtqy5tIkpLqNLFzt+jcFw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}