SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cc93c466e8184423bbfc312bf3a2d9d344b77b83087d6a2bc0209e8ee790798' 
  AND token = 'ToO0GQSEKnBUE+g19X6WP1bSJ793K8JUH05cBPfQPJ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}