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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '183f8523a7f3612ab2f80da37c222189ff3210810d4f7d7d1a009d923ea6f0e6' 
  AND token = 'vXqeOAPRAByA/P8UmIiC7w05tt6a3ZDB13EVfSNsy4Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}