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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6adcb2de849ca9b19d2dcf4052e2a36b9458d284b133719a0129a22a3646b142' 
  AND token = '4ZxYo8KtxR+18mXGC7QUJgXW5EetgGeGo8O6tpSu4jM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}