SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4d91e15cc564429bdb233ac5b93adeea61522758947a284d413180dac3d31d6' 
  AND token = 'Fp00CM9l+N5RKC7TPHgTZkXNoWoEc4HuroZ0DOl1qYY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}