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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a4fcc1f713c693c131f2bebcbaf9e1bbbeaad22f691095500a0d2d98eac2460' 
  AND token = 'yJor6XlVZpo43/4k7TiNjInWNOoO8Xx5Mz2x6QF6axE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}