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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc75452035a45feeb77088907a4771717242be2ff4a22b17e759ad8ea7a0d285' 
  AND token = 'ExlNf9w5REmrep62UMyp2PPNp47O41RDrZ2bU0uRDKw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}