SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1613f605a672cab291b42e3bb14dc8a56f256281ac4d965d12c2ec9c82bb1d51' 
  AND token = 'LVA49pJPyWAusUCrlaBbCF8ZUnocR+c8L0lJGd+bI4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}