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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b65c4f7fe424e795a205bfa424c6a98bae0930de2fdf6c85839041ddf1532179' 
  AND token = 'gdlx3H/I2DfPJekGi/iHLpl4Qr8w7SXgn4rI4hR2b50=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}