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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3ff333a30b19230ec9a902cf78784a415317c56891d3ec72a3dc506382f8c78' 
  AND token = '4ExQiC5kXexKSm14WGsbhJUIjzpfa7DOZpaARgJmS9Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}