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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef9746c07f3cceda05bb37d46681760b11d1ecd26e4aa018dcd546ce758255c4' 
  AND token = 'yYk1nkRy6HskQ/slSmMAI3a0adLgrmZ217UwG3q8Ryw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}