SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8de80c0ccdeaa2c8462f6af4a4389b7cbc3961b49074af09bb02344827a62c1c' 
  AND token = 'dMFG0LH8UkNmxo552flkhpzY9Rfj1LTmTESQChHQxLQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}