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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1957c580c6cbfa8f8b905729df9fa2b3b8bb6af7d02e587289dc8707b00e8b7' 
  AND token = 'pHScUPM7VZwkI1XwsevQY2cCeQ5fcJiE/QnFEwW4t60=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}