SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5136bae7d56ec5d5e18c18c7e7d93e76999d861e25942d2b0ad054570d253a3d' 
  AND token = 'VZpNH9t9hhwNlw+vEG/ZZQIUia+3grmRBqm3xQ8aDj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}