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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0580e370035417cb46c92fa47cbbc10f4629734cb884eeef5b1ca5c19a6d0bed' 
  AND token = 'dqe2hY0eUEQ4n6oDkYUVkbBJdtl7KKpqAT6RRe6fMvU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}