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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42bd92a623d9effc5d56ceac8950501bba01dee3d317c3147b90d4182ba4f271' 
  AND token = '460gXN/fTZbizfOE99JSfublFBlX+rpwzA0w5Wbui3E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}