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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '866c7ed37b9b8d54456a49edd59a9c588d3db06d5b7b9d83fb54f364044f7894' 
  AND token = 'skZ8nSTOH/PGf7djevclDCf9y5rxWcE82v0QeW3J34s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}