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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '721127a8c4bbdce3c32fd9fdc55f4e92942cf90cd9d690ce6bfbd0064c12c60f' 
  AND token = 'uEURdYt58AYgS8oGUy1VN10wJVQrld26Ugm4ams2gnM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}