SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edb118f1cb29882b0084dab00c6998bdc582c7e647b607623987359a4d6ea2e0' 
  AND token = 'vWsaLHtN6gVkxaxsAS2PWKAKI9+To9tZ3KKlgimytCk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}