SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28a154810d0418afad5c8efc5efec9fcbd5f783c442da0aac796d7f4a8fde288' 
  AND token = 'wVIa4/uh2UJ7SXVFWzR7+6YdtPfuQo4fqzFGFNJEmig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}