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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca29557c1d7fdf10cb36fac68ecf615b203815b524335d234f22049b5ae5179a' 
  AND token = 'LfH/u/iZ6Zsfv0eT3RdPqAFls54qsw9I5Kf1v/PC2KY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}