SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21c54c93682f17102ebd58bc0f390c9b8a7f7bb5258a701396561eac7c798e34' 
  AND token = 'N6Evgkt8GBtjRFhkM/jKyLi9F1WZx7Mc08pcc3tDVvA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}