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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6250d8dbb04edb713bc81ce0953ae5584c25c5a7e87be709b358e006a151bb2c' 
  AND token = 'aNAvB8ETQljyhj9FBHl8rVfru1lXitUdJ8BhfccLONc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}