SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e9e28b416b18f452217637beb637249f6fc267533f9af4b1fbaceee970d67e9' 
  AND token = 'rvhDzn+pJn1L8e7PDViyreU9uqmgQc4Y+mI6yofmIYA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}