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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42f60b292d36b88b4098d0194ccc8b86bda2fbabd639de4cb4453ec415a95c21' 
  AND token = 'lKKQMIzqs45rthXbBaRwoPZeeb7aeVxcD2+Bk4lo/S0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}