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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21edb320d6d5c91413b79f1c05fb0414ecffcc2827a78d4d0f0ff8c2188f0895' 
  AND token = 'KdGdH7q63rau9u/tcIqM1cdkRLZklEHM0zRZG57JLSg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}